New Roots Herbal Active Folate - Helps reduce the risk of neural tube defects when taken prior to conception and during early pregnancy. It also enables the body to metabolize carbohydrates, fats, and proteins for cells to easily assimilate and use for energy creation within the mitochondria. Supplementing with active folic acid is important, as many people have impaired function of the enzyme that transforms regular folic acid to this active form the body easily recognizes. This formula includes vitamin B12 and B6 in the bioactive forms methylcobalamin and pyridoxal-5-phosphate (P5P), that serve as cofactors for metabolic reactions throughout the body.