Natural Factors MSM - 1000 mg - Bonus Size - Methyl-sulfonyl-methane (MSM) relieves joint pain naturally by helping the body form healthy connective tissue in joints and muscles. It is also used to make the collagen needed for healthy skin, hair, and nails. MSM may improve a person’s mobility by slowing the breakdown of cartilage, enhancing the body’s inflammatory response, and stimulating the formation of new joint and connective tissues. Improved mobility means a better quality of life, improved athletic ability, joint flexibility, and comfort. Natural Factors MSM uses OptiMSM, the premium form of MSM, certified for quality and consistency and used in clinical studies of efficacy and safety. Supplementing the diet with MSM supports healthy active lifestyles, benefits the connective tissues and reduced pain associated with osteoarthritis.